Looks like D-Wave has a developer kit setup for Python, as outlined in this tutorial on their site: http://www.dwavesys.com/en/dev-tutorial-finance.html. Looks like they realized the same thing I did: to really be applicable for the commercial environment quantum computers need to be programmed via frameworks and not new quantum specific languages.
When I started work on Cove I actually started doing the implementation in both Python and C#. I quickly realized that was creating a lot of unnecessary work for myself and quickly abandoned the Python implementation. My reason for settling on C# was largely that the libraries could be used by multiple languages. However, I still think Python is a great candidate- Python's readability and simple learning curve make it a natural choice.